PAX2A Antikörper (Middle Region)

Produktnummer ABIN2792620

Der Kaninchen Polyklonal Anti-PAX2A-Antikörper wurde für WB und IHC validiert. Er ist geeignet, PAX2A in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Kaninchen, Schaf und Meerschweinchen zu detektieren.

Kurzübersicht für PAX2A Antikörper (Middle Region) (ABIN2792620)

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Kaninchen, Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PAX2A Antikörper

Bindungsspezifität: Middle Region

Sequenz: VSSASNDPVG SYSINGILGI PRSNGEKRKR DEDVSEGSVP NGDSQSGVDS

Kreuzreaktivität: Huhn, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PAX2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PAX2

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-PAX2 Antibody Titration: 1.0 µg/mL
ELISA Titer: 1:312500
Positive Control: Human Liver.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 417 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PAX2A

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Andere Bezeichnung: PAX2

Hintergrund: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.
Protein Interaction Partner: BBS7, BBS4, BBS2, BBS1, RB1, BRCA1, SFRP2, PAXIP1, WT1, MAPK8IP1, MAPK8, ID2,
Protein Size: 417

Molekulargewicht: 45 kDa

Gen-ID: 5076

NCBI Accession: NM_003988, NP_003979

UniProt: Q02962

Pathways: Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation