IRF8 Antikörper (N-Term)

Produktnummer ABIN2792612

Der Kaninchen Polyklonal anti-IRF8 Antikörper wird verwendet zum Nachweis von IRF8 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC.

Kurzübersicht für IRF8 Antikörper (N-Term) (ABIN2792612)

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-IRF8 Antikörper

Bindungsspezifität: N-Term

Sequenz: MFRIPWKHAG KQDYNQEVDA SIFKAWAVFK GKFKEGDKAE PATWKTRLRC

Kreuzreaktivität: Hund, Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IRF8. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 426 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Andere Bezeichnung: IRF8 / ICSBP1

Hintergrund: Interferon consensus sequence-binding protein (Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Alias Symbols: ICSBP, IRF-8, ICSBP1, H-ICSBP
Protein Interaction Partner: SPI1, IRF1, TOP1, ZBTB17, PDGFRB, CBL, UBC, COPS4, COPS5, COPS6, COPS2, MID1, IRF6, GPS1, CDK4, SQSTM1, TRAF6, SMURF2, IRF2, TRIM21, IRF8, ETV6, RELA, NFKB1,
Protein Size: 426

Molekulargewicht: 48 kDa

Gen-ID: 3394

NCBI Accession: NM_002163, NP_002154

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin