SOX9 Antikörper (N-Term)
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- Target Alle SOX9 Antikörper anzeigen
- SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SOX9 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PCPSGSGSDT ENTRPQENTF PKGEPDLKKE SEEDKFPVCI REAVSQVLKG
- Kreuzreaktivität
- Rind (Kuh), Hund, Huhn, Human, Maus, Ratte (Rattus)
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SOX9. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SOX9
- Top Product
- Discover our top product SOX9 Primärantikörper
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- Applikationshinweise
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WB Suggested Anti-SOX9 Antibody Titration: 2.5 µg/mL
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Kommentare
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Antigen size: 509 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))
- Andere Bezeichnung
- SOX9 (SOX9 Produkte)
- Synonyme
- CMD1 antikoerper, CMPD1 antikoerper, SRA1 antikoerper, LOC100227849 antikoerper, 2010306G03Rik antikoerper, AV220920 antikoerper, mKIAA4243 antikoerper, SOX-9 antikoerper, cmd1 antikoerper, cmpd1 antikoerper, sox-9 antikoerper, sox9 antikoerper, sox9-a antikoerper, sox9-b antikoerper, sox9b antikoerper, sra1 antikoerper, SRY-box 9 antikoerper, transcription factor SOX-9 antikoerper, SRY (sex determining region Y)-box 9 antikoerper, SRY box 9 antikoerper, SRY-box 9 L homeolog antikoerper, SOX9 antikoerper, LOC100227849 antikoerper, Sox9 antikoerper, sox9.L antikoerper
- Hintergrund
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SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Alias Symbols: CMD1, SRA1, CMPD1
Protein Interaction Partner: ZBTB7A, SCX, HERC1, UBC, SOX9, ATP6V1H, ctnnb1-a, RUNX2, SMAD3, SMAD2, EP300, CREB3L4, SPEN, KPNB1, TRAF2, CREBBP, MED12, NR5A1, MAF, HSPA1A, CREB1,
Protein Size: 509 - Molekulargewicht
- 56 kDa
- Gen-ID
- 6662
- NCBI Accession
- NM_000346, NP_000337
- UniProt
- P48436
- Pathways
- EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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