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SOX9 Antikörper (N-Term)

Dieser Anti-SOX9 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von SOX9 in WB. Geeignet für Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio) und Ziege.
Produktnummer ABIN2792587

Kurzübersicht für SOX9 Antikörper (N-Term) (ABIN2792587)

Target

Alle SOX9 Antikörper anzeigen
SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Reaktivität

  • 184
  • 77
  • 60
  • 20
  • 7
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Ziege

Wirt

  • 131
  • 54
Kaninchen

Klonalität

  • 96
  • 89
Polyklonal

Konjugat

  • 81
  • 12
  • 7
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser SOX9 Antikörper ist unkonjugiert

Applikation

  • 121
  • 64
  • 56
  • 45
  • 41
  • 27
  • 27
  • 21
  • 20
  • 18
  • 10
  • 7
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 24
    • 16
    • 16
    • 12
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    PCPSGSGSDT ENTRPQENTF PKGEPDLKKE SEEDKFPVCI REAVSQVLKG

    Kreuzreaktivität

    Rind (Kuh), Hund, Huhn, Human, Maus, Ratte (Rattus)

    Homologie

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against SOX9. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human SOX9
  • Applikationshinweise

    WB Suggested Anti-SOX9 Antibody Titration: 2.5 µg/mL
    ELISA Titer: 1:12500
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 509 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

    Andere Bezeichnung

    SOX9

    Hintergrund

    SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
    Alias Symbols: CMD1, SRA1, CMPD1
    Protein Interaction Partner: ZBTB7A, SCX, HERC1, UBC, SOX9, ATP6V1H, ctnnb1-a, RUNX2, SMAD3, SMAD2, EP300, CREB3L4, SPEN, KPNB1, TRAF2, CREBBP, MED12, NR5A1, MAF, HSPA1A, CREB1,
    Protein Size: 509

    Molekulargewicht

    56 kDa

    Gen-ID

    6662

    NCBI Accession

    NM_000346, NP_000337

    UniProt

    P48436

    Pathways

    EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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