RORA Antikörper (N-Term)

Produktnummer ABIN2792585

Der Kaninchen Polyklonal anti-RORA Antikörper wird verwendet zum Nachweis von RORA in Proben von Human und Rind (Kuh). Er wurde validiert für WB.

Kurzübersicht für RORA Antikörper (N-Term) (ABIN2792585)

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Reaktivität: Human, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RORA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: RORA Antibody - N-terminal region

Sequenz: ARKSEPPAPV RRQSYSSTSR GISVTKKTHT SQIEIIPCKI CGDKSSGIHY

Kreuzreaktivität: Human

Homologie: Cow: 100%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RORA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RORA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RORA

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Andere Bezeichnung: RORA

Hintergrund:

Background Information: RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.

Gene Name: RAR-related orphan receptor A

Alternative Symbols: ROR1, ROR2, ROR3, RZRA, NR1F1, IDDECA, RZR-ALPHA

Protein Name: Retinoid-related orphan receptor alpha EMBL BAH02285.1

Molekulargewicht: 59kDa

Gen-ID: 6095

NCBI Accession: NP_599023

UniProt: B6ZGS4

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha