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HOXA10 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HOXA10 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Hund und Kaninchen und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2792574

Kurzübersicht für HOXA10 Antikörper (N-Term) (ABIN2792574)

Target

Alle HOXA10 Antikörper anzeigen
HOXA10 (Homeobox A10 (HOXA10))

Reaktivität

  • 42
  • 28
  • 19
  • 7
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Hund, Kaninchen

Wirt

  • 48
  • 2
Kaninchen

Klonalität

  • 50
Polyklonal

Konjugat

  • 18
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HOXA10 Antikörper ist unkonjugiert

Applikation

  • 43
  • 20
  • 14
  • 13
  • 13
  • 8
  • 5
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 16
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    MSCSESPAAN SFLVDSLISS GRGEAGGGGG GAGGGGGGGY YAHGGVYLPP

    Kreuzreaktivität

    Human, Maus, Kaninchen, Ratte (Rattus)

    Homologie

    Dog: 85%, Human: 92%, Mouse: 78%, Rabbit: 85%

    Produktmerkmale

    This is a rabbit polyclonal antibody against HOXA10. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human HOXA10
  • Applikationshinweise

    WB Suggested Anti-HOXA10 Antibody Titration: 1.25 µg/mL
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 393 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ko, Lengyel, Naora: "The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions." in: Molecular and cellular endocrinology, Vol. 317, Issue 1-2, pp. 112-9, (2010) (PubMed).

  • Target

    HOXA10 (Homeobox A10 (HOXA10))

    Andere Bezeichnung

    HOXA10 / HOX1H

    Hintergrund

    In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA10 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment.
    Alias Symbols: PL, HOX1, HOX1H, HOX1.8
    Protein Interaction Partner: SPI1, COPS5, CREBBP, PBX1, SNAPC1, EMX1, POLR3D, SIRT2, GMNN, EP300, MEIS1, PTPN6, HOXA10, FOXO1,
    Protein Size: 393

    Molekulargewicht

    41 kDa

    Gen-ID

    3206

    NCBI Accession

    NM_018951, NP_061824

    UniProt

    P31260
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