SOX8 Antikörper (C-Term)

Produktnummer ABIN2792566

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SOX8 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund und Pferd.

Kurzübersicht für SOX8 Antikörper (C-Term) (ABIN2792566)

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SOX8 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SOX8 Antibody - C-terminal region

Sequenz: ASPTETGPPR PHIKTEQPSP GHYGDQPRGS PDYGSCSGQS SATPAAPAGP

Kreuzreaktivität: Hund, Human, Maus, Ratte (Rattus)

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 78%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SOX8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SOX8

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Andere Bezeichnung: SOX8

Hintergrund:

Background Information: SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).

Gene Name: SRY (sex determining region Y)-box 8

Alternative Symbols: MGC24837

Protein Name: Transcription factor SOX-8

Molekulargewicht: 47kDa

Gen-ID: 30812

NCBI Accession: NP_055402

UniProt: P57073

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development