SOX8 Antikörper (C-Term)

Produktnummer ABIN2792566

Produktdetails anti-SOX8 Antikörper

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ASPTETGPPR PHIKTEQPSP GHYGDQPRGS PDYGSCSGQS SATPAAPAGP

Kreuzreaktivität: Hund, Human, Maus, Ratte (Rattus)

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 78%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SOX8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:12500
Positive Control: Hela cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 446 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SOX8

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Andere Bezeichnung: SOX8 (SOX8 Produkte)

Hintergrund: SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
Alias Symbols: MGC24837
Protein Interaction Partner: JAM2, PIDD1, NOD1, UBC, MMP1, SOX2, HOXC11, UTF1, PAX3, OLIG2, HHEX, POU3F3, TCF12, DLX5, SP1, NR5A1, JUN, POU5F1, EGR2, CEBPA,
Protein Size: 446

Molekulargewicht: 47 kDa

Gen-ID: 30812

NCBI Accession: NM_014587, NP_055402

UniProt: P57073

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development