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RGS10 Antikörper (Middle Region)

Der Kaninchen Polyklonal Anti-RGS10-Antikörper wurde für WB und FACS validiert. Er ist geeignet, RGS10 in Proben von Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen zu detektieren.
Produktnummer ABIN2792213

Kurzübersicht für RGS10 Antikörper (Middle Region) (ABIN2792213)

Target

Alle RGS10 Antikörper anzeigen
RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Reaktivität

  • 26
  • 12
  • 9
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt

  • 26
  • 3
Kaninchen

Klonalität

  • 27
  • 2
Polyklonal

Konjugat

  • 22
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RGS10 Antikörper ist unkonjugiert

Applikation

  • 19
  • 13
  • 7
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    DQIFNLMKYD SYSRFLKSDL FLKHKRTEEE EEDLPDAQTA AKRASRIYNT

    Homologie

    Cow: 81%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 90%, Rat: 90%

    Produktmerkmale

    This is a rabbit polyclonal antibody against RGS10. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human RGS10
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 181 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

    Andere Bezeichnung

    RGS10

    Hintergrund

    RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G(I)-ALPHA and G(Z)- alpha but fails to interact with the structurally and functionally distinct G(S)-alpha subunit. Activity on G(Z)-alpha is inhibited by palmitoylation of the G-protein.
    Protein Interaction Partner: UBC, ADRB2, APP, PRKACA, GNAI3, GNAO1, GNAI1, GNAZ, GNRHR, CALM1, ACP6, SAP18, EIF6,
    Protein Size: 181

    Molekulargewicht

    21 kDa

    Gen-ID

    6001

    NCBI Accession

    NM_001005339, NP_001005339

    UniProt

    Q96GN0

    Pathways

    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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