CCL18 Antikörper (Middle Region)

Produktnummer ABIN2792202

Produktdetails anti-CCL18 Antikörper

Target: CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PQKFIVDYSE TSPQCPKPGV ILLTKRGRQI CADPNKKWVQ KYISDLKLNA

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CCL18. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCL18

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 89 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CCL18 Antikörper (ABIN2792202)

Schraufstatter, Takamori, Sikora, Sriramarao, DiScipio: "Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 286, Issue 3, pp. L494-501, (2004) (PubMed).

Details zu CCL18

Target: CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

Andere Bezeichnung: CCL18 (CCL18 Produkte)

Synonyme: H7AP1 antikoerper, PARC antikoerper, RP3-330M21.2 antikoerper, AMAC-1 antikoerper, AMAC1 antikoerper, CKb7 antikoerper, DC-CK1 antikoerper, DCCK1 antikoerper, MIP-4 antikoerper, SCYA18 antikoerper, cullin 9 antikoerper, C-C motif chemokine ligand 18 antikoerper, CUL9 antikoerper, CCL18 antikoerper

Hintergrund: CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by CCL18 displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.
Alias Symbols: CKb7, PARC, AMAC1, DCCK1, MIP-4, AMAC-1, DC-CK1, SCYA18
Protein Interaction Partner: C14orf1, UNC119, CRMP1, TLE1, TP53, EEF1A1,
Protein Size: 89

Molekulargewicht: 10 kDa

Gen-ID: 6362

NCBI Accession: NM_002988, NP_002979

UniProt: P55774