CCL18 Antikörper (Middle Region)
Kurzübersicht für CCL18 Antikörper (Middle Region) (ABIN2792202)
Target
Alle CCL18 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- PQKFIVDYSE TSPQCPKPGV ILLTKRGRQI CADPNKKWVQ KYISDLKLNA
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Homologie
- Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CCL18. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CCL18
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 89 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 286, Issue 3, pp. L494-501, (2004) (PubMed).
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: "Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 286, Issue 3, pp. L494-501, (2004) (PubMed).
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- CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
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Andere Bezeichnung
- CCL18
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Hintergrund
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CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by CCL18 displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.
Alias Symbols: CKb7, PARC, AMAC1, DCCK1, MIP-4, AMAC-1, DC-CK1, SCYA18
Protein Interaction Partner: C14orf1, UNC119, CRMP1, TLE1, TP53, EEF1A1,
Protein Size: 89 -
Molekulargewicht
- 10 kDa
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Gen-ID
- 6362
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NCBI Accession
- NM_002988, NP_002979
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UniProt
- P55774
Target
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