CCR4 Antikörper (Middle Region)

Produktnummer ABIN2792190

Dieses Anti-CCR4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCR4 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh) und Hund.

Kurzübersicht für CCR4 Antikörper (Middle Region) (ABIN2792190)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CCR4 Antikörper

Bindungsspezifität: Middle Region

Sequenz: TERNHTYCKT KYSLNSTTWK VLSSLEINIL GLVIPLGIML FCYSMIIRTL

Homologie: Cow: 87%, Dog: 87%, Human: 100%, Mouse: 87%, Rat: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against CCR4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCR4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 360 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Andere Bezeichnung: CCR4

Hintergrund: CCR4 belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1657 BC071751.1 1-1657
Alias Symbols: CC-CKR-4, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293, CD194
Protein Interaction Partner: CCL22, CCL17, CCL5, CCL3, ADRBK2, ADRBK1,
Protein Size: 360

Molekulargewicht: 41 kDa

Gen-ID: 1233

NCBI Accession: NM_005508, NP_005499

UniProt: P51679