CCL13 Antikörper (Middle Region)

Produktnummer ABIN311734

Produktdetails anti-CCL13 Antikörper

Target: CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KSYVITTSRC PQKAVIFRTK LGKEICADPK EKWVQNYMKH LGRKAHTLKT

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CCL13. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCL13

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 98 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CCL13

Target: CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))

Andere Bezeichnung: CCL13 (CCL13 Produkte)

Hintergrund: Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL13 displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis.This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis.
Alias Symbols: CKb10, MCP-4, MGC17134, NCC-1, NCC1, SCYA13, SCYL1
Protein Interaction Partner: APP, ACKR2, ACKR4, HNRNPH3, CCR5, CCR3, CCR2, MMP3, MMP1,
Protein Size: 98

Molekulargewicht: 11 kDa

Gen-ID: 6357

NCBI Accession: NM_005408, NP_005399

UniProt: Q99616

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Phosphorylierungen bei SARS-CoV-2 Infektion