Cyclin G1 Antikörper (N-Term)

Produktnummer ABIN2792152

Der Kaninchen Polyklonal Anti-Cyclin G1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Cyclin G1 in Proben von Human, Maus, Ratte, Rind (Kuh), Schwein und Hund zu detektieren.

Kurzübersicht für Cyclin G1 Antikörper (N-Term) (ABIN2792152)

Target: Cyclin G1 (CCNG1)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin G1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Cyclin G1 Antikörper

Bindungsspezifität: N-Term

Sequenz: IEVLTTTDSQ KLLHQLNALL EQESRCQPKV CGLRLIESAH DNGLRMTARL

Homologie: Cow: 100%, Dog: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CCNG1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCNG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 295 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cyclin G1

Target: Cyclin G1 (CCNG1)

Andere Bezeichnung: CCNG1

Hintergrund: The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. CCNG1 is a member of the cyclin family and contains the cyclin box. It lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: CCNG
Protein Interaction Partner: KRTAP10-7, SPERT, KRT40, LZTS2, HMBOX1, PAK7, TFIP11, RBPMS, TNIP1, PNMA1, SHKBP1, PLEKHA4, TFAP2C, NFATC4, LTBP3, GRN, APP, UBC, CDK2, TP73, TP53, PPP2CA, GAK, PPP2R4, CDKN2A, COX2, MDM2, CDK5,
Protein Size: 295

Molekulargewicht: 34 kDa

Gen-ID: 900

NCBI Accession: NM_004060, NP_004051

UniProt: P51959

Pathways: p53 Signalweg