14-3-3 eta Antikörper (N-Term)

Produktnummer ABIN2792143

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-14-3-3 eta Antikörper wird verwendet zum Nachweis von 14-3-3 eta in Proben von Human, Kaninchen, Hund und Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC.

Kurzübersicht für 14-3-3 eta Antikörper (N-Term) (ABIN2792143)

Target: 14-3-3 eta (YWHAH)

Reaktivität: Human, Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 14-3-3 eta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-14-3-3 eta Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: YWHAH Antibody - N-terminal region

Sequenz: ADGNEKKLEK VKAYREKIEK ELETVCNDVL SLLDKFLIKN CNDFQYESKV

Homologie: Dog: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 78%

Produktmerkmale: This is a rabbit polyclonal antibody against YWHAH. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-14-3-3 eta Antikörper (ABIN2792143)

Ubl, Berg, Holzmann, Krüger, Berger, Arzberger, Bornemann, Riess: "14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta." in: Brain research. Molecular brain research, Vol. 108, Issue 1-2, pp. 33-9, (2002) (PubMed).

Details zu 14-3-3 eta

Target: 14-3-3 eta (YWHAH)

Andere Bezeichnung: YWHAH

Hintergrund:

Background Information: The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

Alternative Symbols: YWHA1

Protein Name: 14-3-3 protein eta

Molekulargewicht: 28kDa

Gen-ID: 7533

NCBI Accession: NP_003396

UniProt: Q04917

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction