14-3-3 eta Antikörper (N-Term)

Produktnummer ABIN2792143

Der Kaninchen Polyklonal Anti-14-3-3 eta-Antikörper wurde für WB und IHC validiert. Er ist geeignet, 14-3-3 eta in Proben von Human, Kaninchen, Hund und Zebrafisch (Danio rerio) zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für 14-3-3 eta Antikörper (N-Term) (ABIN2792143)

Target: 14-3-3 eta (YWHAH)

Reaktivität: Human, Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 14-3-3 eta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-14-3-3 eta Antikörper

Bindungsspezifität: N-Term

Sequenz: ADGNEKKLEK VKAYREKIEK ELETVCNDVL SLLDKFLIKN CNDFQYESKV

Homologie: Dog: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 78%

Produktmerkmale: This is a rabbit polyclonal antibody against YWHAH. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 246 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-14-3-3 eta Antikörper (ABIN2792143)

Ubl, Berg, Holzmann, Krüger, Berger, Arzberger, Bornemann, Riess: "14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta." in: Brain research. Molecular brain research, Vol. 108, Issue 1-2, pp. 33-9, (2002) (PubMed).

Details zu 14-3-3 eta

Target: 14-3-3 eta (YWHAH)

Andere Bezeichnung: YWHAH

Hintergrund: The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: YWHA1
Protein Interaction Partner: DTL, HUWE1, ABL1, SIK3, SUMO2, IRS4, CBL, UBC, UBFD1, EIF5, TBCB, CAPNS1, ALDH7A1, UBE2R2, ISOC1, FERMT2, YWHAQ, PDIA4, YWHAZ, YWHAG, YWHAE, XPO1, VCL, SNRPD2, PCYT2, PTMA, PAK2, PAFAH1B1, MYO1E, HNRNPK, HMGB3, GSS, GNAI3, G6PD, PPP1CA, MARK3, LRRK2, SAV1
Protein Size: 246

Molekulargewicht: 28 kDa

Gen-ID: 7533

NCBI Accession: NM_003405, NP_003396

UniProt: Q04917

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction