TIAL1 Antikörper (C-Term)

Produktnummer ABIN2792137

Der Kaninchen Polyklonal anti-TIAL1 Antikörper (ABIN2792137) detektiert spezifisch TIAL1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio) und Meerschweinchen.

Kurzübersicht für TIAL1 Antikörper (C-Term) (ABIN2792137)

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TIAL1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TIAL1 Antibody - C-terminal region

Sequenz: WNQQGFGVDQ SPSAAWMGGF GAQPPQGQAP PPVIPPPNQA GYGMASYQTQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%, Zebrafish: 76%

Produktmerkmale: This is a rabbit polyclonal antibody against TIAL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TIAL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TIAL1

Target: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Andere Bezeichnung: TIAL1

Hintergrund:

Background Information: The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif.

Gene Name: TIA1 cytotoxic granule-associated RNA binding protein-like 1

Alternative Symbols: TCBP, TIAR

Protein Name: Nucleolysin TIAR

Molekulargewicht: 42 kDa

Gen-ID: 7073

NCBI Accession: NP_003243

UniProt: Q01085