Histone 3 Antikörper (N-Term)
Kurzübersicht für Histone 3 Antikörper (N-Term) (ABIN2792108)
Target
Alle Histone 3 (H3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MARTKQTARK STGGKAPRKQ LATKVARKSA PATGGVKKPH RYRPGTVALR
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Produktmerkmale
- This is a rabbit polyclonal antibody against HIST3H3. It was validated on Western Blot.
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HIST3H3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 136 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Histone 3 (H3) (Histone H3 (H3))
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Andere Bezeichnung
- HIST3H3
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Hintergrund
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Alias Symbols: H3.4, H3/g, H3FT, H3t, MGC126886, MGC126888
Protein Interaction Partner: RAD6, SETD7, WHSC1L1, PRDM2, WHSC1, KMT2A, PHF7, CBX5, TRIM28, ING2, UBC, K07C5.3, APLF, UHRF1, NEDD8, CUL4A, EZH2, ASF1B, ASF1A, MMS22L, IGSF8, TONSL, ICAM1, CD81, AURKA, MLLT1, TAF8, TAF3, TAF9B, PHF21A, ING4, PRAME, KAT6B, CBX6, PHF8, PHF2, ITGA4, TAF1
Protein Size: 136 -
Molekulargewicht
- 15 kDa
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Gen-ID
- 8290
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NCBI Accession
- NM_003493, NP_003484
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UniProt
- P84243
Target
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