DSCR3 Antikörper (Middle Region)
Kurzübersicht für DSCR3 Antikörper (Middle Region) (ABIN2792078)
Target
Alle DSCR3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- VPS26C Antibody - middle region
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Sequenz
- SAPQKGKFTP SPVDFTITPE TLQNVKERAL LPKFLLRGHL NSTNCVITQP
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Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against DSCR3. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human DSCR3
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73191-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DSCR3 (Down Syndrome Critical Region Gene 3 (DSCR3))
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Andere Bezeichnung
- VPS26C
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Hintergrund
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Background Information: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and cognitive disability. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.
Gene Name: VPS26 endosomal protein sorting factor C
Alternative Symbols: DCRA, DSCR3, DSCRA
Protein Name: Down syndrome critical region protein 3
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Molekulargewicht
- 33kDa
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Gen-ID
- 10311
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NCBI Accession
- XP_011527725
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UniProt
- O14972
Target
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