Sorbs2 Antikörper (Middle Region)

Produktnummer ABIN2792074

Produktdetails anti-Sorbs2 Antikörper

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sorbs2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRPRDRSSTE KHDWDPPDRK VDTRKFRSEP RSIFEYEPGK SSILQHERPA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SORBS2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SORBS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Andere Bezeichnung: SORBS2 (Sorbs2 Produkte)

Synonyme: Argbp2 antikoerper, 2010203O03Rik antikoerper, 9430041O17Rik antikoerper, A530071H08 antikoerper, mKIAA0777 antikoerper, argbp2 antikoerper, pro0618 antikoerper, 9430041O17RIK antikoerper, DKFZp468F1119 antikoerper, ARGBP2 antikoerper, PRO0618 antikoerper, sorbin and SH3 domain containing 2 antikoerper, Sorbs2 antikoerper, SORBS2 antikoerper, sorbs2 antikoerper

Hintergrund: SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1.
Alias Symbols: ARGBP2, PRO0618
Protein Interaction Partner: ATPAF2, SH2D4A, VPS37C, EFS, SORBS2, NCK2, YWHAE, WAS, SUZ12, YWHAB, BAG3, HCVgp1, YWHAZ, MDM2, AKT2, nef, WASF1, ADAM15, PTPN12, ABL1, ACTN1, PALLD, SEMA6A, NR1H2, EGFR, DLGAP4, DLGAP1, DLGAP2, SYNJ1, FLOT1, PAK2, RPL9, PAK1, TRAF4, PTK2B, VCL, PKM, CBL,
Protein Size: 644

Molekulargewicht: 70 kDa

Gen-ID: 8470

NCBI Accession: NM_001145670, NP_001139142