Sorbs2 Antikörper (Middle Region)
Kurzübersicht für Sorbs2 Antikörper (Middle Region) (ABIN2792074)
Target
Alle Sorbs2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Middle Region
-
Sequenz
- LRPRDRSSTE KHDWDPPDRK VDTRKFRSEP RSIFEYEPGK SSILQHERPA
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against SORBS2. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human SORBS2
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeat freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))
-
Andere Bezeichnung
- SORBS2
-
Hintergrund
-
SORBS2 is an adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. It can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1.
Alias Symbols: ARGBP2, PRO0618
Protein Interaction Partner: ATPAF2, SH2D4A, VPS37C, EFS, SORBS2, NCK2, YWHAE, WAS, SUZ12, YWHAB, BAG3, HCVgp1, YWHAZ, MDM2, AKT2, nef, WASF1, ADAM15, PTPN12, ABL1, ACTN1, PALLD, SEMA6A, NR1H2, EGFR, DLGAP4, DLGAP1, DLGAP2, SYNJ1, FLOT1, PAK2, RPL9, PAK1, TRAF4, PTK2B, VCL, PKM, CBL,
Protein Size: 644 -
Molekulargewicht
- 70 kDa
-
Gen-ID
- 8470
-
NCBI Accession
- NM_001145670, NP_001139142
Target
-