GCM2 Antikörper (N-Term)

Produktnummer ABIN2792067

Produktdetails anti-GCM2 Antikörper

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HSGYPVTNFW RLDGNAIFFQ AKGVHDHPRP ESKSETEARR SAIKRQMASF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GCM2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GCM2

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GCM2

Target: GCM2 (Glial Cells Missing Homolog 2 (GCM2))

Andere Bezeichnung: GCM2 (GCM2 Produkte)

Synonyme: GCMb antikoerper, Gcm-2 antikoerper, gcm-2 antikoerper, GCMB antikoerper, hGCMb antikoerper, Gcm-rs1 antikoerper, Gcm1 antikoerper, Gcm1-rs2 antikoerper, glial cells missing homolog 2 antikoerper, glial cells missing homolog 2 (Drosophila) antikoerper, glial cells missing homolog 2 S homeolog antikoerper, GCM2 antikoerper, gcm2 antikoerper, gcm2.S antikoerper, Gcm2 antikoerper

Hintergrund: This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.
Alias Symbols: GCMB, hGCMb
Protein Interaction Partner: HSFY1, RBPMS, FHL3, CRX,
Protein Size: 506

Molekulargewicht: 57 kDa

Gen-ID: 9247

NCBI Accession: NM_004752, NP_004743

UniProt: O75603