TXN Antikörper (C-Term)

Produktnummer ABIN2792061

Der Kaninchen Polyklonal anti-TXN Antikörper (ABIN2792061) detektiert spezifisch TXN in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen, Pferd und Schaf.

Kurzübersicht für TXN Antikörper (C-Term) (ABIN2792061)

Target: TXN (Thioredoxin (TXN))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TXN Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TXN Antibody - C-terminal region

Sequenz: NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TXN. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TXN

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72618-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TXN

Target: TXN (Thioredoxin (TXN))

Andere Bezeichnung: TXN

Hintergrund:

Background Information: TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. It nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. It induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55)

Alternative Symbols: TRX, TRDX, TRX1, Trx80

Molekulargewicht: 11kDa

Gen-ID: 7295

NCBI Accession: NP_003320

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis