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TXN Antikörper (C-Term)
TXN
Reaktivität: Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2792061
Produktdetails anti-TXN Antikörper
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Target
Alle TXN Antikörper anzeigen
TXN
(Thioredoxin (TXN))
Bindungsspezifität
Alle Epitope für TXN Antikörper
C-Term
Reaktivität
Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf
Wirt
Alle Wirte für TXN Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TXN Antikörper
Polyklonal
Konjugat
Alle Konjugate für TXN Antikörper
Dieser TXN Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TXN Antikörper
Western Blotting (WB), Immunohistochemistry (IHC)
Sequenz
NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT
Homologie
Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
Produktmerkmale
This is a rabbit polyclonal antibody against TXN. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human TXN
Top Product
Discover our top product TXN Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu TXN
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Target
TXN
(Thioredoxin (TXN))
Andere Bezeichnung
TXN (TXN Produkte )
Synonyme
TRDX antikoerper, TRX antikoerper, TRX1 antikoerper, ADF antikoerper, AW550880 antikoerper, Trx1 antikoerper, Txn antikoerper, trx antikoerper, TXN antikoerper, SCM1.18 antikoerper, trxA3 antikoerper, thioredoxin antikoerper, TR-1 antikoerper, Trx-1 antikoerper, thioredoxin antikoerper, thioredoxin 1 antikoerper, thioredoxin L homeolog antikoerper, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) antikoerper, thioredoxin pseudogene antikoerper, cytosolic thioredoxin Trx1 antikoerper, TXN antikoerper, Txn1 antikoerper, txn.L antikoerper, txn antikoerper, trx antikoerper, SCO0885 antikoerper, PHG25ORF099c antikoerper, LOC100349046 antikoerper, Txn antikoerper, trx1 antikoerper
Hintergrund
TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. It nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. It induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55) Alias Symbols: TRDX, TRX, TRX1 Protein Interaction Partner: NR3C1, GPX1, APEX1, SRP9, PARK2, TXNIP, UBD, Melk, NPM1, PAN2, UBL4A, UBC, DYNLT1, SIAH1, NFE2, MYD88, MYC, MLH1, IFIT3, CDKN1A, ACTN4, GPRASP2, HCVgp1, PRDX1, MAP3K5, SFXN1, UBL5, UBQLN4, TAX1BP3, AHCYL1, SSSCA1, SYNCRIP, WDR1, ATP6V1F, UBE2V1, UBE2D2, S Protein Size: 105
Molekulargewicht
11 kDa
Gen-ID
7295
NCBI Accession
NM_003329 , NP_003320
UniProt
P10599
Pathways
Carbohydrate Homeostasis , Cell RedoxHomeostasis
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