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MVB12B Antikörper (C-Term)

MVB12B Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2791520
  • Target Alle MVB12B Antikörper anzeigen
    MVB12B (Multivesicular Body Subunit 12B (MVB12B))
    Bindungsspezifität
    C-Term
    Reaktivität
    Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd
    Wirt
    • 2
    Kaninchen
    Klonalität
    • 2
    Polyklonal
    Konjugat
    • 2
    Dieser MVB12B Antikörper ist unkonjugiert
    Applikation
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    HISLTLPATF RGRNSTRTDY EYQHSNLYAI SAMDGVPFMI SEKFSCVPES
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against MVB12B. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human MVB12B
    Top Product
    Discover our top product MVB12B Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MVB12B (Multivesicular Body Subunit 12B (MVB12B))
    Andere Bezeichnung
    MVB12B (MVB12B Produkte)
    Synonyme
    C9orf28 antikoerper, FAM125B antikoerper, 2610200O14Rik antikoerper, 2610528K11Rik antikoerper, AI414895 antikoerper, Fam125b antikoerper, RGD1309709 antikoerper, fam125b antikoerper, mvb12b antikoerper, fam125ba antikoerper, zgc:152929 antikoerper, multivesicular body subunit 12B antikoerper, multivesicular body subunit 12B S homeolog antikoerper, multivesicular body subunit 12Ba antikoerper, MVB12B antikoerper, Mvb12b antikoerper, mvb12b.S antikoerper, mvb12ba antikoerper
    Hintergrund
    The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: C9orf28, MVB12B
    Protein Interaction Partner: LNX1, gag, UBC, VPS37A, MVB12A, TSG101,
    Protein Size: 319
    Molekulargewicht
    35 kDa
    Gen-ID
    89853
    NCBI Accession
    NM_033446, NP_258257
    UniProt
    Q9H7P6
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