MVB12B Antikörper (C-Term)

Produktnummer ABIN2791520

Der Kaninchen-Polyklonal Anti-MVB12B-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von MVB12B in Proben aus Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd und Kaninchen. }

Kurzübersicht für MVB12B Antikörper (C-Term) (ABIN2791520)

Target: MVB12B (Multivesicular Body Subunit 12B (MVB12B))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MVB12B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MVB12B Antikörper

Bindungsspezifität: C-Term

Sequenz: HISLTLPATF RGRNSTRTDY EYQHSNLYAI SAMDGVPFMI SEKFSCVPES

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MVB12B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MVB12B

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MVB12B

Target: MVB12B (Multivesicular Body Subunit 12B (MVB12B))

Andere Bezeichnung: MVB12B

Hintergrund: The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: C9orf28, MVB12B
Protein Interaction Partner: LNX1, gag, UBC, VPS37A, MVB12A, TSG101,
Protein Size: 319

Molekulargewicht: 35 kDa

Gen-ID: 89853

NCBI Accession: NM_033446, NP_258257

UniProt: Q9H7P6