DRAXIN Antikörper (C-Term)

Produktnummer ABIN2791412

Produktdetails anti-DRAXIN Antikörper

Target: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Bindungsspezifität: C-Term

Reaktivität: Human, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRAXIN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TLDMALFDWT DYEDLKPDGW PSAKKKEKHR GKLSSDGNET SPAEGEPCDH

Homologie: Cow: 86%, Dog: 93%, Horse: 100%, Human: 100%, Pig: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DRAXIN. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DRAXIN

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 349 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DRAXIN

Target: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Andere Bezeichnung: DRAXIN (DRAXIN Produkte)

Hintergrund: DRAXIN is a chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. It acts as a chemorepulsive guidance protein for commissural axons during development and is able to inhibit or repel neurite outgrowth from dorsal spinal cord. DRAXIN inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
Alias Symbols: AGPA3119, UNQ3119, neucrin
Protein Size: 349

Molekulargewicht: 36 kDa

Gen-ID: 374946

NCBI Accession: NM_198545, NP_940947

UniProt: Q8NBI3