DENND1C Antikörper (C-Term)

Produktnummer ABIN2790995

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DENND1C in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DENND1C Antikörper (C-Term) (ABIN2790995)

Target: DENND1C (DENN/MADD Domain Containing 1C (DENND1C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DENND1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DENND1C Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: DENND1C Antibody - C-terminal region

Sequenz: PSSLEDPRAR PPKALLAERA HLQPREEPGA LNSPATPTSN CQKSQPSSRP

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DENND1C. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND1C

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68265-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DENND1C

Target: DENND1C (DENN/MADD Domain Containing 1C (DENND1C))

Andere Bezeichnung: DENND1C

Hintergrund:

Background Information: Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.

Alternative Symbols: FAM31C

Protein Name: DENN domain-containing protein 1C

Molekulargewicht: 87kDa

Gen-ID: 79958

NCBI Accession: NP_079174

UniProt: Q8IV53