PARPBP Antikörper (C-Term)

Produktnummer ABIN2790948

Der Kaninchen Polyklonal anti-PARPBP Antikörper wird verwendet zum Nachweis von PARPBP in Proben von Human, Pferd, Kaninchen, Schwein und Ratte. Er wurde validiert für WB.

Kurzübersicht für PARPBP Antikörper (C-Term) (ABIN2790948)

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Reaktivität: Human, Pferd, Kaninchen, Schwein, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARPBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PARPBP Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PARPBP Antibody - C-terminal region

Sequenz: YMENDLSEGV NPSVGRSTIG TSFGNVHLDR SKNEKVSRKS TSQTGNKSSK

Homologie: Horse: 85%, Human: 100%, Pig: 92%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PARPBP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP68105-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PARPBP

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Andere Bezeichnung: PARPBP

Hintergrund:

Background Information: PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. PARPBP antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly(A) homopolymers and positively regulate the poly(ADP-ribosyl)ation activity of PARP1, however such function may be indirect.

Gene Name: PARP1 binding protein

Alternative Symbols: AROM, PARI, C12orf48

Protein Name: PCNA-interacting partner

Molekulargewicht: 32kDa

Gen-ID: 55010

UniProt: Q9NWS1