ANAPC15 Antikörper (N-Term)
Kurzübersicht für ANAPC15 Antikörper (N-Term) (ABIN2790945)
Target
Alle ANAPC15 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Sequenz
- EETELQQQEQ QHQAWLQSIA EKDNNLVPIG KPASEHYDDE EEEDDEDDED
-
Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 90%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against ANAPC15. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ANAPC15
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 121 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- ANAPC15 (Anaphase Promoting Complex Subunit 15 (ANAPC15))
-
Andere Bezeichnung
- ANAPC15
-
Hintergrund
-
ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.
Alias Symbols: APC15, C11orf51
Protein Interaction Partner: ANAPC4, CDC26, ANAPC1, ANAPC7, ANAPC5, ANAPC2, ANAPC10, CDC16, CDC23, CDC27, CDC20,
Protein Size: 121 -
Molekulargewicht
- 13 kDa
-
Gen-ID
- 25906
-
NCBI Accession
- NM_014042, NP_054761
-
UniProt
- P60006
Target
-