TTI2 Antikörper (N-Term)

Produktnummer ABIN2790934

Produktdetails anti-TTI2 Antikörper

Target: TTI2 (TELO2 Interacting Protein 2 (TTI2))

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: THSLEQPWTT PRSREVAREV LTSLLQVTEC GSVAGFLHGE NEDEKGRLSV

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 75%, Horse: 100%, Human: 100%, Pig: 92%, Rabbit: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against TTI2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TTI2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 508 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TTI2

Target: TTI2 (TELO2 Interacting Protein 2 (TTI2))

Andere Bezeichnung: TTI2 (TTI2 Produkte)

Synonyme: C8orf41 antikoerper, TELO2 interacting protein 2 antikoerper, TTI2 antikoerper, Tti2 antikoerper

Hintergrund: TTI2 is a regulator of the DNA damage response (DDR). 'TTI2 is part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). 'TTI2, together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
Alias Symbols: C8orf41
Protein Interaction Partner: FUS, UBC, SUMO1, NEDD8, EGFR, ELAVL1, RPAP3, PIH1D1, RUVBL2, TELO2, TTI1, RUVBL1, PRKDC, HSP90AA1, HSPA4,
Protein Size: 508

Molekulargewicht: 56 kDa

Gen-ID: 80185

NCBI Accession: NM_025115, NP_079391

UniProt: Q6NXR4