YOD1 Antikörper (N-Term)

Produktnummer ABIN2790891

Der Kaninchen Polyklonal anti-YOD1 Antikörper wird verwendet zum Nachweis von YOD1 in Proben von Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) und Rind (Kuh). Er wurde validiert für WB.

Kurzübersicht für YOD1 Antikörper (N-Term) (ABIN2790891)

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YOD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-YOD1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Yod1 Antibody - N-terminal region

Sequenz: VPQSEAGTKA GPAGGRPADT MWRVRCKAKG GTHLLQGLSS RTRLRELQGQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against Yod1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Yod1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67915-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu YOD1

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Andere Bezeichnung: Yod1

Hintergrund:

Background Information: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Yod1 may act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Yod1 mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. It is able to cleave both polyubiquitin and di-ubiquitin.

Gene Name: YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)

Alternative Symbols: Hshin7, 6330564D18Rik, 9930028C20Rik

Protein Name: Ubiquitin thioesterase OTU1

Molekulargewicht: 38 kDa

Gen-ID: 226418

NCBI Accession: NP_848806

UniProt: Q8CB27

Pathways: ER-Nucleus Signaling