YOD1 Antikörper (N-Term)

Produktnummer ABIN2790891

Produktdetails anti-YOD1 Antikörper

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YOD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VPQSEAGTKA GPAGGRPADT MWRVRCKAKG GTHLLQGLSS RTRLRELQGQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against Yod1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Yod1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu YOD1

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Andere Bezeichnung: Yod1 (YOD1 Produkte)

Hintergrund: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Yod1 may act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Yod1 mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. It is able to cleave both polyubiquitin and di-ubiquitin.
Alias Symbols: 9930028C20Rik, Hshin7
Protein Size: 343

Molekulargewicht: 37 kDa

Gen-ID: 226418

NCBI Accession: NM_178691, NP_848806

UniProt: Q8CB27

Pathways: ER-Nucleus Signaling