AFG1-Like ATPase (AFG1L) (N-Term) Antikörper

Produktnummer ABIN2790804

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AFG1-Like ATPase in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Hund, Meerschweinchen, Pferd und Ratte.

Kurzübersicht für AFG1-Like ATPase (AFG1L) (N-Term) Antikörper (ABIN2790804)

Target: AFG1-Like ATPase (AFG1L)

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: N-Term

Verwendungszweck: AFG1L Antibody - N-terminal region

Sequenz: HGPLDHYDFL IKAHELKDDE HQRRVIQCLQ KLHEDLKGYN IEAEGLFSKL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against LACE1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human LACE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67628-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: AFG1-Like ATPase (AFG1L)

Andere Bezeichnung: AFG1L

Hintergrund:

Background Information: This gene encodes a mitochondrial integral membrane protein that plays a role in mitochondrial protein homeostasis. The protein contains a P-loop motif and a five-domain structure that is conserved in fly, yeast, and bacteria. It functions to mediate the degradation of nuclear-encoded complex IV subunits. Two conserved estrogen receptor binding sites are located within 2.5 kb of this gene. Polymorphisms in this gene have been associated with bipolar disorder. Alternative splicing results in multiple transcript variants.

Gene Name: AFG1 like ATPase

Alternative Symbols: AFG1, LACE1, c222389

Protein Name: AFG1-like ATPase

Molekulargewicht: 53kDa

Gen-ID: 246269

NCBI Accession: NP_660358

UniProt: Q8WV93