CCDC99 Antikörper (C-Term)
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- Target Alle CCDC99 Antikörper anzeigen
- CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CCDC99 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PRLAAESKLQ TEVKEGKETS SKLEKETCKK LHPILYVSSK STPETQCPQQ
- Homologie
- Cow: 79%, Dog: 93%, Horse: 92%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CCDC99. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCDC99
- Top Product
- Discover our top product CCDC99 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 605 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))
- Andere Bezeichnung
- CCDC99 (CCDC99 Produkte)
- Synonyme
- CCDC99 antikoerper, CG15415 antikoerper, Dmel\\CG15415 antikoerper, SPINDLY antikoerper, ccdc99 antikoerper, 1700018I02Rik antikoerper, 2600001J17Rik antikoerper, 2810049B11Rik antikoerper, AA409762 antikoerper, Ccdc99 antikoerper, RGD1306908 antikoerper, ccdc99-a antikoerper, ccdc99-b antikoerper, spdl1-a antikoerper, spdl1-b antikoerper, spdl1 antikoerper, spindle apparatus coiled-coil protein 1 antikoerper, CG15415 gene product from transcript CG15415-RB antikoerper, Tetratricopeptide repeat (TPR)-like superfamily protein antikoerper, spindle apparatus coiled-coil protein 1 L homeolog antikoerper, spindle apparatus coiled-coil protein 1 S homeolog antikoerper, SPDL1 antikoerper, Spindly antikoerper, SPY antikoerper, spdl1 antikoerper, Spdl1 antikoerper, spdl1.L antikoerper, spdl1.S antikoerper
- Hintergrund
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CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. CCDC99 is also required for correct spindle orientation. It does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
Alias Symbols: FLJ20364, FLJ40690, CCDC99
Protein Interaction Partner: RTP5, PPP1R18, DYX1C1, SPDL1, USP15, TRAF4, CA8, NEK9, SIRT1, HMGCS1, DHX40, YLPM1, SF3B3, ITSN1, UBC, KIAA1377, GPS2,
Protein Size: 605 - Molekulargewicht
- 67 kDa
- Gen-ID
- 54908
- NCBI Accession
- NM_017785, NP_060255
- UniProt
- Q96EA4
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