ATXN7L3 Antikörper (Middle Region)

Produktnummer ABIN2790607

Dieses Anti-ATXN7L3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ATXN7L3 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für ATXN7L3 Antikörper (Middle Region) (ABIN2790607)

Target: ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATXN7L3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATXN7L3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: MNKSESDQED NDDINDNDWS YGSEKKAKKR KSDKLWYLPF QNPNSPRRSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ATXN7L3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ATXN7L3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 354 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATXN7L3

Target: ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))

Andere Bezeichnung: ATXN7L3

Hintergrund: ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Alias Symbols: DKFZp761G2113
Protein Interaction Partner: SIRT1, USP22, SECISBP2, SERTAD1, PICK1, USP6, UCHL3, HIST2H2BE, HIST2H2AC, ATXN7, KAT2A, ENY2, TAF5L, SUPT3H, TRRAP, TAF10,
Protein Size: 354

Molekulargewicht: 38 kDa

Gen-ID: 56970

NCBI Accession: NM_020218, NP_064603

UniProt: Q14CW9