ATF7IP2 Antikörper (N-Term)

Produktnummer ABIN2790606

Der Kaninchen Polyklonal Anti-ATF7IP2-Antikörper wurde für WB validiert. Er ist geeignet, ATF7IP2 in Proben von Human zu detektieren.

Kurzübersicht für ATF7IP2 Antikörper (N-Term) (ABIN2790606)

Target: ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATF7IP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATF7IP2 Antikörper

Bindungsspezifität: N-Term

Sequenz: EEIVHSETKL EQVVCSYQKP SRTTESPSRV FTEEAKDSLN TSENDSEHQT

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATF7IP2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ATF7IP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 543 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATF7IP2

Target: ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))

Andere Bezeichnung: ATF7IP2

Hintergrund: ATF7IP2 is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. It can both act as an activator or a repressor depending on the context. ATF7IP2 mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity.
Alias Symbols: FLJ12668, MCAF2
Protein Interaction Partner: SETDB1, SP1, MBD1,
Protein Size: 543

Molekulargewicht: 59 kDa

Gen-ID: 80063

NCBI Accession: NM_001256160, NP_001243089

UniProt: Q5U623