IYD Antikörper (N-Term)

Produktnummer ABIN2790550

Dieses Anti-IYD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IYD in WB. Geeignet für Human, Ratte, Rind (Kuh), Hund und Kaninchen.

Kurzübersicht für IYD Antikörper (N-Term) (ABIN2790550)

Target: IYD (Iodotyrosine Deiodinase (IYD))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IYD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IYD Antikörper

Bindungsspezifität: N-Term

Sequenz: NADRSMEKKK GEPRTRAEAR PWVDEDLKDS SDLHQAEEDA DEWQESEENV

Homologie: Cow: 77%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against IYD. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IYD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 247 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IYD

Target: IYD (Iodotyrosine Deiodinase (IYD))

Andere Bezeichnung: IYD

Hintergrund: This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4.
Alias Symbols: C6orf71, DEHAL1, TDH4, dJ422F24.1
Protein Interaction Partner: TRIM69,
Protein Size: 247

Molekulargewicht: 27 kDa

Gen-ID: 389434

NCBI Accession: NM_001164695, NP_001158167

Pathways: Thyroid Hormone Synthesis