DAND5 Antikörper (C-Term)

Produktnummer ABIN2790536

Produktdetails anti-DAND5 Antikörper

Target: DAND5 (DAN Domain Family, Member 5 (DAND5))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAND5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YIPGSDPTPL VLCNSCMPAR KRWAPVVLWC LTGSSASRRR VKISTMLIEG

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DAND5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DAND5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 189 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DAND5

Target: DAND5 (DAN Domain Family, Member 5 (DAND5))

Andere Bezeichnung: DAND5 (DAND5 Produkte)

Hintergrund: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
Alias Symbols: CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, MGC126849, SP1
Protein Size: 189

Molekulargewicht: 21 kDa

Gen-ID: 199699

NCBI Accession: NM_152654, NP_689867

UniProt: Q8N907