DAND5 Antikörper (N-Term)

Produktnummer ABIN2790535

Der Kaninchen Polyklonal anti-DAND5 Antikörper (ABIN2790535) detektiert spezifisch DAND5 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DAND5 Antikörper (N-Term) (ABIN2790535)

Target: DAND5 (DAN Domain Family, Member 5 (DAND5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAND5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DAND5 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: DAND5 Antibody - N-terminal region

Sequenz: SGALPTGSGR PEPQSPRPQS WAAANQTWAL GPGALPPLVP ASALGSWKAF

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DAND5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DAND5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66786-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DAND5

Target: DAND5 (DAN Domain Family, Member 5 (DAND5))

Andere Bezeichnung: DAND5

Hintergrund:

Background Information: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Alternative Symbols: SP1, CER2, COCO, CRL2, CERL2, DANTE, GREM3, CKTSF1B3

Protein Name: DAN domain family member 5

Molekulargewicht: 21kDa

Gen-ID: 199699

NCBI Accession: NP_689867

UniProt: Q8N907