SNX15 Antikörper (N-Term)

Produktnummer ABIN2790379

Der Kaninchen Polyklonal anti-SNX15 Antikörper wird verwendet zum Nachweis von SNX15 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Pferd, Meerschweinchen und Schwein. Er wurde validiert für WB.

Kurzübersicht für SNX15 Antikörper (N-Term) (ABIN2790379)

Target: SNX15 (Sorting Nexin 15 (SNX15))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SNX15 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SNX15 Antibody - N-terminal region

Sequenz: RKLHGDLAYT HRNLFRRLEE FPAFPRAQVF GRFEASVIEE RRKGAEDLLR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SNX15. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SNX15

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66279-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SNX15

Target: SNX15 (Sorting Nexin 15 (SNX15))

Andere Bezeichnung: SNX15

Hintergrund:

Background Information: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Alternative Symbols: HSAF001435

Protein Name: Sorting nexin-15 Ensembl ENSP00000316410 EMBL ADP91255.1

Molekulargewicht: 29kDa

Gen-ID: 29907

NCBI Accession: NP_680086

UniProt: E5KQS6