STAG2 Antikörper (C-Term)
Kurzübersicht für STAG2 Antikörper (C-Term) (ABIN2790312)
Target
Alle STAG2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- LLAGGDDDTM SVISGISSRG STVRSKKSKP STGKRKVVEG MQLSLTEESS
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against STAG2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human STAG2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 1231 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- STAG2 (Stromal Antigen 2 (STAG2))
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Andere Bezeichnung
- STAG2
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Hintergrund
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STAG2 is a component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
Alias Symbols: DKFZp686P168, DKFZp781H1753, FLJ25871, SA-2, SA2, bA517O1.1, SCC3B
Protein Interaction Partner: UBC, CDCA5, HDAC8, VCP, SRRM2, RBM14, SFPQ, RAD21, PLK1, NHP2L1, NSMCE2, UBD, SIRT7, SUMO2, SMC3, SMC1A, PDS5A, PDS5B, Stag2, WAPAL, WFDC5, SSU72, SRRM1, STAG1,
Protein Size: 1231 -
Molekulargewicht
- 141 kDa
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Gen-ID
- 10735
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NCBI Accession
- NM_006603, NP_006594
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UniProt
- Q8N3U4
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Pathways
- Stem Cell Maintenance
Target
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