FOLR2 Antikörper (C-Term)

Produktnummer ABIN2790292

Der Kaninchen Polyklonal anti-FOLR2 Antikörper (ABIN2790292) detektiert spezifisch FOLR2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein und Kaninchen.

Kurzübersicht für FOLR2 Antikörper (C-Term) (ABIN2790292)

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOLR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FOLR2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: FOLR2 Antibody - C-terminal region

Sequenz: LCEGLWSHSY KVSNYSRGSG RCIQMWFDSA QGNPNEEVAR FYAAAMHVNA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FOLR2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FOLR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65891-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Andere Bezeichnung: FOLR2

Hintergrund:

Background Information: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.

Alternative Symbols: FBP, FOLR1, FR-P3, FRbeta, FR-BETA, BETA-HFR, FBP/PL-1

Protein Name: Folate receptor beta

Molekulargewicht: 31 kDa

Gen-ID: 2350

NCBI Accession: NP_000794

UniProt: P14207

Pathways: Dicarboxylic Acid Transport