STXBP4 Antikörper (N-Term)

Produktnummer ABIN2790280

Der Kaninchen Polyklonal anti-STXBP4 Antikörper wird verwendet zum Nachweis von STXBP4 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für STXBP4 Antikörper (N-Term) (ABIN2790280)

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STXBP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STXBP4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: STXBP4 Antibody - N-terminal region

Sequenz: SVNKESMIGV SFEEAKSIIT GAKLRLESAW EIAFIRQKSD NIQPENLSCT

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against STXBP4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human STXBP4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65839-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu STXBP4

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Andere Bezeichnung: STXBP4

Hintergrund:

Background Information: STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.

Gene Name: Syntaxin binding protein 4

Alternative Symbols: Synip

Protein Name: Syntaxin-binding protein 4

Molekulargewicht: 62kDa

Gen-ID: 252983

NCBI Accession: NP_848604

UniProt: Q6ZWJ1