Importin 8 Antikörper (C-Term)

Produktnummer ABIN2790260

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Importin 8 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Hund, Pferd und Meerschweinchen.

Kurzübersicht für Importin 8 Antikörper (C-Term) (ABIN2790260)

Target: Importin 8 (IPO8)

Reaktivität: Human, Ratte, Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Importin 8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Importin 8 Antikörper

Bindungsspezifität: C-Term

Sequenz: PPAVDAVVGQ IVPSILFLFL GLKQVCATRQ LVNREDRSKA EKADMEENEE

Homologie: Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IPO8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IPO8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 832 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Importin 8

Target: Importin 8 (IPO8)

Andere Bezeichnung: IPO8

Hintergrund: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ26580, RANBP8
Protein Interaction Partner: UBC, EGFR, YWHAE, CBX5, ATXN1, CUL3, Trim28, AGO4, AGO3, AGO2, AGO1, KPNB1, RANGAP1, SRP19, RPL23A,
Protein Size: 832

Molekulargewicht: 96 kDa

Gen-ID: 10526

NCBI Accession: NM_001190995, NP_001177924

UniProt: O15397