SPG21 Antikörper (C-Term)
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- Target Alle SPG21 Antikörper anzeigen
- SPG21 (Spastic Paraplegia 21 (SPG21))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Rind (Kuh), Maus, Kaninchen, Ratte, Schaf, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPG21 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- IPVTIMDVFD QSALSTEAKE EMYKLYPNAR RAHLKTGGNF PYLCRSAEVN
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SPG21. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SPG21
- Top Product
- Discover our top product SPG21 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 308 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SPG21 (Spastic Paraplegia 21 (SPG21))
- Andere Bezeichnung
- SPG21 (SPG21 Produkte)
- Synonyme
- ACP33 antikoerper, GL010 antikoerper, MAST antikoerper, BM-019 antikoerper, C78576 antikoerper, D9Wsu18e antikoerper, Maspardin antikoerper, wu:fd07h02 antikoerper, zgc:73091 antikoerper, SPG21, maspardin antikoerper, spastic paraplegia 21 (autosomal recessive, Mast syndrome) antikoerper, SPG21, maspardin S homeolog antikoerper, SPG21 antikoerper, Spg21 antikoerper, spg21.S antikoerper, spg21 antikoerper
- Hintergrund
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The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: ACP33, BM-019, GL010, MASPARDIN, MAST
Protein Interaction Partner: INCA1, SPRED2, DTX3L, CMTM5, TRIM9, DTX2, REEP6, FAM114A1, ATPAF2, EFHC2, CCDC33, CCDC102B, TRIM54, AGTRAP, CTPS2, S100B, PRPS1, KRT15, CRYAA, TRIM23, CUTC, ARL6IP1, IKZF3, MID2, RABAC1, TFG, TRAF2, TRAF1, TCF12, TCF4, UBC, GSK3A, DHX40, YLPM1, HMGCS1, AK
Protein Size: 308 - Molekulargewicht
- 35 kDa
- Gen-ID
- 51324
- NCBI Accession
- NM_016630, NP_057714
- UniProt
- Q9NZD8
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