SPG21 Antikörper (C-Term)

Produktnummer ABIN2790233

Der Kaninchen Polyklonal Anti-SPG21-Antikörper wurde für WB validiert. Er ist geeignet, SPG21 in Proben von Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Schaf und Schwein zu detektieren.

Kurzübersicht für SPG21 Antikörper (C-Term) (ABIN2790233)

Target: SPG21 (Spastic Paraplegia 21 (SPG21))

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Schaf, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPG21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPG21 Antikörper

Bindungsspezifität: C-Term

Sequenz: LCRSAEVNLY VQIHLLQFHG TKYAAIDPSM VSAEELEVQK GSLGISQEEQ

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 79%, Rat: 86%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SPG21. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SPG21

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 308 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SPG21

Target: SPG21 (Spastic Paraplegia 21 (SPG21))

Andere Bezeichnung: SPG21

Hintergrund: The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: ACP33, BM-019, GL010, MASPARDIN, MAST
Protein Interaction Partner: INCA1, SPRED2, DTX3L, CMTM5, TRIM9, DTX2, REEP6, FAM114A1, ATPAF2, EFHC2, CCDC33, CCDC102B, TRIM54, AGTRAP, CTPS2, S100B, PRPS1, KRT15, CRYAA, TRIM23, CUTC, ARL6IP1, IKZF3, MID2, RABAC1, TFG, TRAF2, TRAF1, TCF12, TCF4, UBC, GSK3A, DHX40, YLPM1, HMGCS1, AK
Protein Size: 308

Molekulargewicht: 35 kDa

Gen-ID: 51324

NCBI Accession: NM_016630, NP_057714

UniProt: Q9NZD8