SPAG1 Antikörper (C-Term)
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- Target Alle SPAG1 Antikörper anzeigen
- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPAG1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KIEIQEVNEG KEEPGRPAGE VSMGCLASEK GGKSSRSPED PEKLPIAKPN
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SPAG1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SPAG1
- Top Product
- Discover our top product SPAG1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 926 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
- Andere Bezeichnung
- SPAG1 (SPAG1 Produkte)
- Synonyme
- cb1089 antikoerper, MGC162178 antikoerper, wu:fj78g10 antikoerper, sp75 antikoerper, tpis antikoerper, hsd-3.8 antikoerper, HSD-3.8 antikoerper, SP75 antikoerper, TPIS antikoerper, sperm associated antigen 1 antikoerper, sperm associated antigen 1a antikoerper, SPAG1 antikoerper, spag1a antikoerper, CpipJ_CPIJ006297 antikoerper, spag1 antikoerper, Spag1 antikoerper
- Hintergrund
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The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization.
Alias Symbols: FLJ32920, HSD-3.8, SP75, TPIS
Protein Interaction Partner: UBC, GNB1, PCNA, PRKCA, DYT10,
Protein Size: 926 - Molekulargewicht
- 104 kDa
- Gen-ID
- 6674
- NCBI Accession
- NM_003114, NP_003105
- UniProt
- Q07617
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