SPAG1 Antikörper (C-Term)

Produktnummer ABIN2790232

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SPAG1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SPAG1 Antikörper (C-Term) (ABIN2790232)

Target: SPAG1 (Sperm Associated Antigen 1 (SPAG1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPAG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPAG1 Antikörper

Bindungsspezifität: C-Term

Sequenz: KIEIQEVNEG KEEPGRPAGE VSMGCLASEK GGKSSRSPED PEKLPIAKPN

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SPAG1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SPAG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 926 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SPAG1

Target: SPAG1 (Sperm Associated Antigen 1 (SPAG1))

Andere Bezeichnung: SPAG1

Hintergrund: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization.
Alias Symbols: FLJ32920, HSD-3.8, SP75, TPIS
Protein Interaction Partner: UBC, GNB1, PCNA, PRKCA, DYT10,
Protein Size: 926

Molekulargewicht: 104 kDa

Gen-ID: 6674

NCBI Accession: NM_003114, NP_003105

UniProt: Q07617