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SPAG1 Antikörper (N-Term)

SPAG1 Reaktivität: Human, Hund WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2790231
  • Target Alle SPAG1 Antikörper anzeigen
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    Bindungsspezifität
    • 10
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 29
    • 1
    • 1
    Human, Hund
    Wirt
    • 28
    • 1
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPAG1 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 16
    • 16
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    LHVGKEKYSK RPTKKKTPRD YAEWDKFDVE KECLKIDEDY KEKTVIDKSH
    Homologie
    Dog: 85%, Human: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SPAG1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of human SPAG1
    Top Product
    Discover our top product SPAG1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    Andere Bezeichnung
    SPAG1 (SPAG1 Produkte)
    Synonyme
    cb1089 antikoerper, MGC162178 antikoerper, wu:fj78g10 antikoerper, sp75 antikoerper, tpis antikoerper, hsd-3.8 antikoerper, HSD-3.8 antikoerper, SP75 antikoerper, TPIS antikoerper, sperm associated antigen 1 antikoerper, sperm associated antigen 1a antikoerper, SPAG1 antikoerper, spag1a antikoerper, CpipJ_CPIJ006297 antikoerper, spag1 antikoerper, Spag1 antikoerper
    Hintergrund
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
    Alias Symbols: SP75, TPIS, CT140, CILD28, HSD-3.8, HEL-S-268
    Protein Size: 416
    Molekulargewicht
    45 kDa
    Gen-ID
    6674
    NCBI Accession
    NM_003114, NP_003105
    UniProt
    G3XAM3
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