SELPLG Antikörper (C-Term)

Produktnummer ABIN2790195

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SELPLG in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Rind (Kuh), Hund und Meerschweinchen.

Kurzübersicht für SELPLG Antikörper (C-Term) (ABIN2790195)

Target: SELPLG (Selectin P Ligand (SELPLG))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SELPLG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SELPLG Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SELPLG Antibody - C-terminal region

Sequenz: EMVCISSLLP DGGEGPSATA NGGLSKAKSP GLTPEPREDR EGDDLTLHSF

Homologie: Cow: 91%, Dog: 83%, Guinea Pig: 92%, Human: 100%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against SELPLG. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SELPLG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65609-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Andere Bezeichnung: SELPLG

Hintergrund:

Background Information: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

Gene Name: Selectin P ligand

Alternative Symbols: CLA, CD162, PSGL1, PSGL-1

Protein Name: P-selectin glycoprotein ligand 1

Molekulargewicht: 39kDa

Gen-ID: 6404

NCBI Accession: NP_002997

UniProt: Q14242