ARHGAP8 Antikörper (Middle Region)

Produktnummer ABIN2790172

Der Kaninchen Polyklonal Anti-ARHGAP8-Antikörper wurde für WB validiert. Er ist geeignet, ARHGAP8 in Proben von Pferd, Human, Rind (Kuh), Hund, Meerschweinchen, Maus und Ratte zu detektieren.

Kurzübersicht für ARHGAP8 Antikörper (Middle Region) (ABIN2790172)

Target: ARHGAP8 (rho GTPase Activating Protein 8 (ARHGAP8))

Reaktivität: Pferd, Human, Rind (Kuh), Hund, Meerschweinchen, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARHGAP8 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PRPPLPTQQF GVSLQYLKDK NQGELIPPVL RFTVTYLREK GLRTEGLFRR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARHGAP8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ARHGAP8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 433 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARHGAP8

Target: ARHGAP8 (rho GTPase Activating Protein 8 (ARHGAP8))

Andere Bezeichnung: ARHGAP8

Hintergrund: This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
Alias Symbols: BPGAP1, FLJ20185, PP610
Protein Interaction Partner: UBC, SH3GL1, RHOA, CDC42, BNIP2, ARHGAP1, ARHGAP8, CTTN, RAC1,
Protein Size: 433

Molekulargewicht: 50 kDa

Gen-ID: 23779

NCBI Accession: NM_181335, NP_851852

UniProt: Q86XV6